Postinflammatory hyperpigmentation
https://en.wikipedia.org/wiki/Hyperpigmentation
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References
Postinflammatory Hyperpigmentation 32644576 NIH
Postinflammatory hyperpigmentation (PIH) ከቆዳ እብጠት ወይም ጉዳት በኋላ የሚከሰት ተደጋጋሚ የቆዳ ችግር ነው። ረዘም ጊዜ የሚቆይ አዝማሚያና ጥቁር የቆዳ ቀለም ያላቸው ሰዎች (Fitzpatrick skin types III–VI) ላይ ይታያል። ምንም እንኳን ብዙ ጊዜ በራሱ ይሻላል፣ ነገርግን ይህ ጊዜ ትንሽ ሊወስድ ይችላል፣ ስለዚህ ህክምና ብዙ ጊዜ ለረጅም ጊዜ ይፈልጋል። የተለያዩ ህክምናዎችን ማጣተር ተገቢ ይሆናል።
Postinflammatory hyperpigmentation (PIH) is a common acquired cutaneous disorder occurring after skin inflammation or injury. It is chronic and is more common and severe in darker-skinned individuals (Fitzpatrick skin types III–VI). While the condition typically improves spontaneously, this process can take months to years, necessitating prolonged treatment. Combination therapy is the most effective.
Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color 20725554 NIH
Postinflammatory hyperpigmentation የተለመደ የቆዳ ለውጥ ተከታይ ነው። ጠቆር ያለ ቆዳ ያላቸው ሰዎች በከፋ እና በተደጋጋሚ የሚደርሰውን ማስተካከያ ይፈልጋሉ። ጥናቶች እንደሚያሳዩ፣ postinflammatory hyperpigmentation ያለው ጉዳይ ጥቁር የቆዳ ቀለም ያለውን ሰው የቆዳ ህክምና እንዲፈልግ የሚያደርገው ከተለያዩ ምክንያቶች አንዱ ነው። ቅድመ ህክምና ለpostinflammatory hyperpigmentation በጣም አስፈላጊ ነው፤ ብዙውን ጊዜ የመጀመሪያውን እብጠት ሁኔታ በማስተዳደር ይጀምራል። የመጀመሪያው የሕክምና መስመር በተለይ ቆዳን ከፀሐይ መከላከያ ጋር የሚያቀርቡ የአካባቢ ወኪሎችን መጠቀም ይጠቀማል። እነዚህ ወኪሎች ከhydroquinone, azelaic acid, kojic acid, arbutin, licorice extracts ጋር በተደጋጋሚ ተጠቅመው ቀለምን በትክክል ይቀንሳሉ። ተጨማሪ የሚውሉት retinoids, mequinol, ascorbic acid, niacinamide, N‑acetyl glucosamine, soy ወኪሎች ደግሞ ቀለም ገላጭ ተግባራቸውን ያሳያሉ፤ አዲስ ህክምናዎች በሚቀጥሉት ዘመናት እየተገነባ ነው። ወቅታዊ ህክምናዎች ብዙውን ጊዜ ለላይ‑ደረጃ hyperpigmentation ውጤታማ ሲሆኑ፣ ለተለያዩ ጉዳዮች (laser, chemical peel) የሚደረጉ ሂደቶች አስፈላጊ ሊሆኑ ይችላሉ። ስለዚህ፣ postinflammatory hyperpigmentation እና ተያያዥ ብስጭትን ለማስወገድ በእነዚህ ህክምናዎች ትክክለኛ እና ተገቢ እንክብካቤ ያድርጉ።
Postinflammatory hyperpigmentation is a common sequelae of inflammatory dermatoses that tends to affect darker skinned patients with greater frequency and severity. Epidemiological studies show that dyschromias, including postinflammatory hyperpigmentation, are among the most common reasons darker racial/ethnic groups seek the care of a dermatologist. The treatment of postinflammatory hyperpigmentation should be started early to help hasten its resolution and begins with management of the initial inflammatory condition. First-line therapy typically consists of topical depigmenting agents in addition to photoprotection including a sunscreen. Topical tyrosinase inhibitors, such as hydroquinone, azelaic acid, kojic acid, arbutin, and certain licorice extracts, can effectively lighten areas of hypermelanosis. Other depigmenting agents include retinoids, mequinol, ascorbic acid, niacinamide, N-acetyl glucosamine, and soy with a number of emerging therapies on the horizon. Topical therapy is typically effective for epidermal postinflammatory hyperpigmentation; however, certain procedures, such as chemical peeling and laser therapy, may help treat recalcitrant hyperpigmentation. It is also important to use caution with all of the above treatments to prevent irritation and worsening of postinflammatory hyperpigmentation.